abstract：:In the last decade, significant progress in the knowledge and management of external genital anomalies has been achieved, including an improved understanding of epidemiology and pathophysiology of these anomalies, the identification of etiologic genetic defects, and significant improvements in surgical approaches that...

journal_title：Pediatric clinics of North America

authors： MacLellan DL,Diamond DA

更新日期：2006-06-01 00:00:00

abstract：:The experience of hypoglycemia is probably the most feared and hated consequence of life with type 1 diabetes among pediatric patients and their parents. Although transient detrimental effects are clearly disturbing and may have severe results, there is surprisingly little evidence of long-term CNS damage, even after ...

journal_title：Pediatric clinics of North America

authors： Ryan C,Gurtunca N,Becker D

更新日期：2005-12-01 00:00:00

abstract：:As a result of their preadoptive histories and experiences, internationally adopted children, especially those with a history of institutionalization, can present with a complex profile of developmental and behavioral issues. Although many children demonstrate significant recovery and resilience after joining their ad...

journal_title：Pediatric clinics of North America

authors： Nalven L

更新日期：2005-10-01 00:00:00

abstract：:An "apparent life-threatening event" (ALTE) refers to an episode that is of concern to the caregiver and is associated with a combination of apnea, color change, change in tone, choking, or gagging. Although the natural history of ALTE is most often benign, there is a risk for subsequent morbidity and mortality. The p...

journal_title：Pediatric clinics of North America

authors： Dewolfe CC

更新日期：2005-08-01 00:00:00

abstract：:Acute pharyngitis is one of the most common illnesses for which children visit primary care physicians. Most cases of acute pharyngitis in children are caused by viruses and are benign and self-limited. Group A beta-hemolytic streptococcus is the most important of the bacterial causes of acute pharyngitis. Strategies ...

journal_title：Pediatric clinics of North America

authors： Gerber MA

更新日期：2005-06-01 00:00:00

abstract：:Human autoinflammatory diseases (except for the periodic fever, adenopathy, pharyngitis, aphthae syndrom) are a heterogeneous group of genetically determined diseases characterized by seemingly unprovoked inflammation, in the absence of autoimmune or infective causes. Tremendous advances in the understanding of these ...

journal_title：Pediatric clinics of North America

authors： Padeh S

更新日期：2005-04-01 00:00:00

abstract：:College-age young women frequently experience a variety of menstrual-related complaints, including dysmenorrheal, menorrhagia, irregular menses, and menstrual-related mood changes. These problems deserve careful evaluation; they may reflect normal ovulatory menstrual symptoms or be suggestive of significant pathology ...

journal_title：Pediatric clinics of North America

authors： Adams Hillard PJ,Deitch HR

更新日期：2005-02-01 00:00:00

abstract：:This article acquaints readers with the data sources documenting the dramatic increases of overweight and obesity in the United States in the past 40 years, explains the reference standards for ascertaining measures of overweight in adults and children, and cites evidence that establishes obesity as a risk factor for ...

journal_title：Pediatric clinics of North America

authors： Clinton Smith J

更新日期：2004-12-01 00:00:00

abstract：:This article focuses on the current status of in utero catheter interventions for congenital heart disease. The discussion of fetal interventions for cardiac defects briefly reviews the evolution of approaches to congenital heart disease and issues surrounding the prenatal detection of cardiac defects, the rationale f...

journal_title：Pediatric clinics of North America

authors： Tworetzky W,Marshall AC

更新日期：2004-12-01 00:00:00

abstract：:Sudden cardiac death (SCD) in children is the result of multiple etiologies and treatment (prophylaxis) must be tailored accordingly. In children who do not have congenital heart disease, surgical therapy of SCD typically consists of implantation of an internal defibrillator, with specific attention to the small size ...

journal_title：Pediatric clinics of North America

authors： Jaquiss RD,Tweddell JS,Litwin SB

更新日期：2004-10-01 00:00:00

abstract：:This brief overview serves as an introduction to the vast array of basic and clinical concepts that are pertinent to the basic understanding of ventricular fibrillation, its genesis, and its clinical management. ...

journal_title：Pediatric clinics of North America

authors： Fish FA

更新日期：2004-10-01 00:00:00

abstract：:Neonatal anemia is a condition with a diverse etiologic spectrum.Therefore, in order to form a focused differential diagnosis, it is important for the caregiver to have some knowledge of the more common causes of low hemoglobin and hematocrit concentrations in the neonate. Proper history taking, physical examination, ...

journal_title：Pediatric clinics of North America

authors： Bizzarro MJ,Colson E,Ehrenkranz RA

更新日期：2004-08-01 00:00:00

abstract：:Varicella zoster virus (VZV), herpes simplex virus (HSV) and cytomegalovirus (CMV) are all members of the Herpesviridae family.Humans are the only source of infection for these double stranded DNA viruses. Infants may acquire these infections in utero, peripartum, or postnatally, resulting in a variety of clinical syn...

journal_title：Pediatric clinics of North America

authors： Enright AM,Prober CG

更新日期：2004-08-01 00:00:00

abstract：:This article discusses various anomalies and abnormalities of the umbilical cord and issues related to cord care. The issue of screening newborns with an isolated single umbilical artery for renal abnormalities is addressed. The clinical presentation of infants with omphalomesenteric and urachal duct remants along wit...

journal_title：Pediatric clinics of North America

authors： Pomeranz A

更新日期：2004-06-01 00:00:00

abstract：:Meconium aspiration syndrome is a common problem that most pediatricians will encounter in the delivery room and normal newborn nursery. Approximately 13% of all live births are complicated by meconium-stained amniotic fluid. Like many aspects of the perinatal period, optimal care of an infant born through meconium-st...

journal_title：Pediatric clinics of North America

authors： Gelfand SL,Fanaroff JM,Walsh MC

更新日期：2004-06-01 00:00:00

abstract：:Diagnosis and treatment of CMI is undergoing reexamination that includes redefinition of the anatomic Chiari malformation and refinement and redefinition of the clinical syndrome. Children with SMI present with head pain of some kind, a neurologic deficit, or with signs of spinal cord dysfunction from syrinx. Some wil...

journal_title：Pediatric clinics of North America

authors： Yassari R,Frim D

更新日期：2004-04-01 00:00:00

abstract：:Sleep problems are common in many pediatric medical disorders and complicate management and patient outcomes. A wide range of conditions, including asthma, cystic fibrosis, sickle cell disease, gastroesophageal reflux, neuromuscular diseases, scoliosis, craniofacial abnormalities, obesity, and chromosomal disorders, h...

journal_title：Pediatric clinics of North America

authors： Bandla H,Splaingard M

更新日期：2004-02-01 00:00:00

abstract：:Disorders of excessive sleepiness are uncommon in children. When they occur, the presentation is often consistent with the developmental age of the child and does not meet either historical or laboratory criteria determined with adults in mind. Because of these differences, the true diagnosis can be missed or inadequa...

journal_title：Pediatric clinics of North America

authors： Givan DC

更新日期：2004-02-01 00:00:00

abstract：:The possibility of extending life with advanced medical procedures such as organ transplantation in childhood has made it possible to focus on patients' well-being in a wider perspective. They still experience a high prevalence of medical and physical disabilities, which definitively have an impact on a child's psycho...

journal_title：Pediatric clinics of North America

authors： Qvist E,Jalanko H,Holmberg C

更新日期：2003-12-01 00:00:00

abstract：:Significant advances have been made in the understanding of allograft rejection. There is growing awareness that allograft acceptance, or tolerance, is also an active process rather than a passive absence of rejection. Mechanistic awareness of this process has spawned many preclinical strategies for the prevention of ...

journal_title：Pediatric clinics of North America

authors： Pearl JP,Preston E,Kirk AD

更新日期：2003-12-01 00:00:00

abstract：:Attention-deficit/hyperactivity disorder is the most common neurobehavioral disorder of childhood, with most children maintaining symptoms of ADHD as adolescents and as adults. It is among the most common chronic conditions that primary care pediatricians see. Progress in brain imaging, genetics, neuropsychology, and ...

journal_title：Pediatric clinics of North America

authors： Reiff MI,Stein MT

更新日期：2003-10-01 00:00:00

abstract：:Trauma is prevalent in the lives of children. It derives from many sources, and, depending on its characteristics, can produce transient or enduring and devastating consequences. Early trauma, if left untreated, can set the stage for chronic deficits in the behavioral repertoires of affected children, and thus shape p...

journal_title：Pediatric clinics of North America

authors： Spates CR,Waller S,Samaraweera N,Plaisier B

更新日期：2003-08-01 00:00:00

abstract：:Asthmatic children living in low-income families in United States inner city communities continue to have disproportionately high rates of hospitalizations, emergency department visits, disability, and death. Current research implicates a combination of environmental, biologic, and disease mismanagement factors that u...

journal_title：Pediatric clinics of North America

authors： Federico MJ,Liu AH

更新日期：2003-06-01 00:00:00

abstract：:Although recent clinical trials suggest that conjugate vaccination will be less effective for the prevention of AOM than for IPD, these trials have demonstrated impressive reductions in the incidence of AOM due to invasive and antibiotic-resistant pneumococcal serotypes. These data suggest that if serotype replacement...

journal_title：Pediatric clinics of North America

authors： Weber SM,Grundfast KM

更新日期：2003-04-01 00:00:00

abstract：:Most ocular and orbital tumors of childhood are distinct from tumors that occur in adults. Many are congenital with early presentations. Most pediatric orbital tumors are benign; developmental cysts comprise half of orbital cases, with capillary hemangioma being the second most common orbital tumor. The most common or...

journal_title：Pediatric clinics of North America

authors： Castillo BV Jr,Kaufman L

更新日期：2003-02-01 00:00:00

abstract：:A palpable mass in the abdomen of a child is a serious finding. In this article the authors present their single-institution experience of how these malignancies present and their distribution by age and diagnosis. The most common abdominal malignancies diagnosed in the pediatric population include neuroblastoma, Wilm...

journal_title：Pediatric clinics of North America

authors： Golden CB,Feusner JH

更新日期：2002-12-01 00:00:00

abstract：:This article outlines a few of the hematologic problems that are particular to developing countries, particularly those of the tropics. Because of globalization and the increasing movement of populations, hematologists in wealthier countries must be aware of the general patterns of hematologic change in the important ...

journal_title：Pediatric clinics of North America

authors： Weatherall DJ,Kwiatkowski D

更新日期：2002-12-01 00:00:00

abstract：:This review discusses disorders of altered neutrophil number and function and provide a basic framework for patient evaluation and management. The sections begin with neutropenia, neutrophilia and neutrophil dysfunction with a general screening approach to differentiate common, more benign syndromes from rare, often m...

journal_title：Pediatric clinics of North America

authors： Kyono W,Coates TD

更新日期：2002-10-01 00:00:00

abstract：:Infections occur in childhood and adolescent athletes just as they do in all children and adolescents. Because of the sports environment, and in some instances the sport itself, athletes can be prone to infections that will alter their athletic performance or present risks to other athletes. Recognition of the infecti...

journal_title：Pediatric clinics of North America

authors： Buescher ES

更新日期：2002-08-01 00:00:00

abstract：:Chronic musculoskeletal pain is becoming increasingly common in young athletes. When these athletes do not respond well to standard treatments, for example physical theraphy and anti-inflammatories, other diagnoses must be considered, such as reflex sympathetic dystrophy, fibromyalgia, and/or overtraining syndrome. ...

journal_title：Pediatric clinics of North America

authors： Small E

更新日期：2002-06-01 00:00:00

abstract：:More than half of US adolescents will experiment with marijuana. Of those who try marijuana more than once, approximately one third will subsequently use marijuana regularly, although most will have stopped by their late 20s. Although genetic predisposition plays the most important role in determining who will develop...

journal_title：Pediatric clinics of North America

authors： Gruber AJ,Pope HG Jr

更新日期：2002-04-01 00:00:00

abstract：:Feeding disorders are common in infants and children. Multiple interacting behavioral, anatomic, and functional factors all can impact on the feeding process, making the evaluation and treatment of pediatric disorders complex and challenging. Knowledge of the normal process of feeding and swallowing, a careful history...

journal_title：Pediatric clinics of North America

authors： Rudolph CD,Link DT

更新日期：2002-02-01 00:00:00

abstract：:During the past decade, a tremendous wealth of information regarding the pathogenesis, genetics, and therapy of IBD has been discovered. Judging by the number of new publications published every month in scientific journals and the great enthusiasm at scientific meetings, this outstanding pace surely will continue. In...

journal_title：Pediatric clinics of North America

authors： Mamula P,Mascarenhas MR,Baldassano RN

更新日期：2002-02-01 00:00:00

abstract：:The evaluation and management of adolescents with varicoceles continue to evolve. Current recommendations for repair are based on the findings of impaired testicular growth or spermatogenesis; however, with early evaluation and selective treatment, clinicians should be able to reduce the potential for future fertility...

journal_title：Pediatric clinics of North America

authors： Kass EJ

更新日期：2001-12-01 00:00:00

abstract：:Ultimately, after gathering and assessing all available evidence, pediatricians and health care policymakers must make informed decisions on whether exposure to a specific agent has the potential to cause cancer in children. In the case of DES, for which the results were clear, there was no question that the drug shou...

journal_title：Pediatric clinics of North America

authors： DeBaun MR,Gurney JG

更新日期：2001-10-01 00:00:00

abstract：:Childhood obesity may be seen as a marker for high-risk dietary and physical inactivity practices. Recent increases in the prevalence of overweight and obesity among American children are not limited to one age, gender, or ethnic group, which suggests that unique behaviors of the members of various racial or ethnic su...

journal_title：Pediatric clinics of North America

authors： Crawford PB,Story M,Wang MC,Ritchie LD,Sabry ZI

更新日期：2001-08-01 00:00:00

abstract：:Status epilepticus is a serious medical emergency that requires prompt and appropriate intervention. Maintenance of adequate vital function with attention to airway, breathing, and circulation; prevention of systemic complications; and rapid termination of seizures must be coupled with investigating and treating any u...

journal_title：Pediatric clinics of North America

authors： Hanhan UA,Fiallos MR,Orlowski JP

更新日期：2001-06-01 00:00:00

abstract：:Breastfeeding generates numerous questions. Every call about breastfeeding received over the telephone is an opportunity for health care professionals to listen and support the caller and offer factual information and advice to help the family to have an enjoyable breastfeeding experience. ...

journal_title：Pediatric clinics of North America

authors： Philipp BL

更新日期：2001-04-01 00:00:00

abstract：:Given the importance of iron nutrition during the first year of life, there are surprisingly few true, randomized, controlled studies addressing this issue; however, it seems that iron deficiency is unlikely in full-term, breastfed infants during the first 6 months of life because these infants' body iron stores are s...

journal_title：Pediatric clinics of North America

authors： Griffin IJ,Abrams SA

更新日期：2001-04-01 00:00:00

abstract：:Although breastfeeding is well accepted as the optimal method of infant feeding, the US failed to reach the goals set for the year 2000. Support from employers, health insurers, health providers, and society are required to reach the goals set forth in Healthy People 2010-75% of mothers initiate breastfeeding, 50% of ...

journal_title：Pediatric clinics of North America

authors： Ball TM,Bennett DM

更新日期：2001-02-01 00:00:00